Mots-Clés

single-cell, breast cancer, epigenetics

Description

The Vallot Lab is a creatuve research group in UMR3244/Translational Department, Institut Curie (Paris, FR). Our lab aims in understanding epigenomic tumor evolution and leverage its reversibility to enhance response to standard of cares and intercept tumor initiation. We have established a unique expertise in epigenetics and RNA sequencing, bioinformatics analyses and advanced genetic engineering. To this aim, we have developed single cell epigenomic methods and analysis of such data and generated several multi-modal epigenomic datasets studying the mammary gland in normal and tumor states.1,2,3 (Github) We are lucky to be embedded near hospital, which favours translational discoveries. More info on the lab missions on our website and github/vallotlab.

Training and tech skills:

PhD in Bioinformatics, Computational Biology or bioengineer (Grande Ecole) graduate, with strong programming skills (Python, R, Perl, SQL or Java) and interest in genetic tools and single cell epigenomic and transcriptomic data analysis. On-the-job training will complement your skills.

Abilities and soft skills:

You are passionate about biology, very well organized, and able to work efficiently in an international environment. You are proactive, take your own initiative, and can work independently but also as part of a small group.

>> We are seeking a creative, motivated and highly independent fellow to lead new research projects in our lab. During the projects you will benefit from access to cutting-edge computational resources and training opportunities, collaborative work environment with opportunity for career advancement and networking with top- ranking institutions (CRCT, CRCI2NA, Weizmann, etc.), biotech companies (Google, One Biosciences, ect.) and Single-Cell Initiative platforms.

Key tasks:
- Develop & implement novel bioinformatics algorithms and tools.
- Generate & analyze transcriptomic datasets.

- Collaborate with experimental biologists to design and interpret experiments.

Type of contract: Permanent contract
Salary: According to current grids and experience
Starting date: As soon as possible
Duration: Up to 6 months CDD followed by immediate CDI CNRS appointment Concours (October 2024) .