Post-Doctorant(e) en Bioinformatique
CDD · Postdoc · 36 mois Bac+8 / Doctorat, Grandes Écoles Institut Pasteur · Paris (France)
Date de prise de poste : 1 janvier 2024
computational biology, gene regulatory elements, gene regulatory networks, human sex determination
Postdoctoral bioinformatics position available for 3 years in the Human Developmental Genetics Unit, Institut Pasteur, Paris, France (https://research.pasteur.fr/en/team/human-developmental-genetics/)
We are seeking a highly motivated individual with a background in quantitative analysis - Computer Science, Mathematics, Computational Biology, or Bioinformatics to conduct research in the computational analysis of human developmental regulatory genomics using the biological process of sex-determination as a model. The candidate will develop deep learning approaches for the accurate prediction of gene regulatory elements (GRE) and networks (GRN), identify disease-related pathogenic variants, and use multiple datasets for the reconstruction of cell‐type specific GREs and GRNs.
The position also offers the possibility of extensive wet-lab experience – e.g., training in state-of-the-art human cellular reprograming and organoid development methods along with the functional analysis of human pathogenic variants.
We expect the candidate to have -
- a strong track record in research as evidenced by peer‐reviewed publications
- research experience in at least two of these fields - regulatory genomics, statistics, evolutionary biology, gene regulation, epigenomics, computational disease genetics, and genomic and epigenomic architectures that determine and maintain cellular identity
- Experience on working with the Encyclopedia of DNA Elements (ENCODE), NIH Roadmap Epigenomics, Ensembl, and other similar databases
- fluency in Python, R, and MATLAB
- experience working with GPU‐based architectures
- ability to communicate effectively and to work independently and as a team member.
- experience in developing deep learning algorithms, methods, and tools
Procédure : Envoyez un e-mail
Date limite : 31 décembre 2023
Dr. Anu Bashamboo / Pr. Ken McElreavey
Offre publiée le 14 novembre 2023, affichage jusqu'au 31 décembre 2023